All biohazard labs are audited by the Research Compliance Auditor using the combined set of criteria. The combined set of criteria lists the references to the Standards and gives an expected method of local implementation within the Supervisor's laboratory.
It is the 'combined set of criteria' document which gives the details of what is expected. It is strongly recommended that the 'combined set of criteria' be reviewed within the laboratory prior to the audit so that any questions can be addressed beforehand.
A printable check/summary sheet is here.
Level 1 criteria are assessed according to the Canadian Biosafety Guideline (Draft Ed). Where standards were not found but the practice is implemented, equivalent standards were chosen from the Laboratory Biosafety Guidelines (3rd Ed), the WHO Laboratory Biosafety Manual (3rd Ed) and the CDC/NIH Biosafety in Microbiological and Biomedical Laboratories (5th Ed).
Level 2 criteria are assessed according to the Canadian Biosafety Standard (2nd Ed).
Level 3 criteria are assessed according to the Canadian Biosafety Standard (2nd Ed).
Plant pest labs (in vitro to greenhouses, where applicable) will also be audited according to the Containment Standards for Facilities Handling Plant Pests.
Aquatic pathogen labs (in vitro and in vivo, where applicable) will also be audited according to the Containment Standards for Facilities Handling Aquatic Animal Pathogens.
As of August 25, 2014, the following laboratory audit schedule will apply:
- Containment Level 1 laboratories to be audited at minimum every three years
- Containment Level 2 laboratories are to be audited at minimum every two years
- Containment Level 3 laboratories are to be audited annually
Laboratory audit results are entered into the BUP system and an email sent to the Supervisor to log in and view/acknowledge the report(s). Due to the nature of shared spaces and a variable number of rooms, a PI may be required to acknowledge more than one audit report. Every effort is made to audit a PI or a group in a reasonsble time frame.The Supervisor is expected to acknowledge within 30 days and is expected to have all deficiencies addressed within a reasonable timeframe. The date the audit result is sent, constitutes Day 0 of Section 8.1 of RMM106 PBAC Terms of Reference - Monitoring of Non-Compliance.
Audit results are reviewed by the PBAC each month. Trends in audit deficiencies are reviewed annually to allow for plan of corrective action to be taken in subseqent years.